TFEA is indispensable in lithium-ion battery development, where it functions as a key component or additive in electrolyte solutions. Its stability helps form a robust solid-electrolyte interphase (SEI) layer, significantly improving battery cycle life and safety. Furthermore, it is a versatile trifluoroacetylation reagent and a high-performance solvent used in pharmaceuticals, agrochemicals, and other specialized chemical synthesis requiring fluorine incorporation.