4'-Hydroxyacetophenone

1-(4-hydroxyphenyl)ethanone

CAS Register Number

99-93-4

EC Number

202-802-8

IUPAC Name

1-(4-hydroxyphenyl)ethanone

Molecular Formula

C8H8O2

Molecular Weight

136.15 g/mol

SMILES

CC(=O)C1=CC=C(C=C1)O

4′-Hydroxyacetophenone (CAS 99-93-4), or p-Hydroxyacetophenone, is a versatile aromatic intermediate with a keto-phenol structure. Widely used as a cosmetic preservative and antioxidant, it also serves as an important flavor and fragrance agent and a key synthetic precursor in the pharmaceutical industry.

Uses of 4'-Hydroxyacetophenone

This multi-functional compound is indispensable across several industries. In Cosmetics, it is CIR-approved, providing robust preservative and stabilizing effects without releasing formaldehyde. As a Flavoring Agent (FEMA 4330), it imparts a pleasant sweet/balsam note to food and beverage products. Furthermore, its reactivity makes it a crucial chemical intermediate for pharmaceutical synthesis, particularly in the production of drugs like Paracetamol (as a reference standard or impurity).

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