(S)-(+)-3-Hydroxytetrahydrofuran

Molecular-Structure-of-S-3-Hydroxytetrahydrofuran-CAS-86087-23-2
(3S)-oxolan-3-ol

CAS Register Number

86087-23-2

EC Number

425-090-2

IUPAC Name

(3S)-oxolan-3-ol

Molecular Formula

C4H8O2

Molecular Weight

88.11 g/mol

SMILES

C1COC[C@H]1O

A crucial chiral building block and fine chemical intermediate. This clear, colorless-to-pale-yellow liquid possesses an active hydroxyl group and an asymmetric carbon center, making it essential for the highly selective synthesis of complex chiral molecules. It serves as a foundational component in high-value organic synthesis.

Uses of (S)-(+)-3-Hydroxytetrahydrofuran

This compound is widely used in the pharmaceutical industry as a versatile intermediate for manufacturing numerous enantiomerically pure drugs. Key applications include the synthesis of antiviral agents (like Amprenavir and Fosamprenavir for HIV), select anti-cancer and antidiabetic medications (such as Empagliflozin and Afatinib). Its utility extends to the development of novel agrochemicals and other fine chemicals requiring a defined stereochemistry.

Packaging

Customized Packaging available upon request

Packaging

Custom packaging configurations are available upon request.

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